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Improvement in Renal Hemodynamics following Combined Angiotensin II Infusion and AT1R Blockade in Aged Female Sheep following Fetal Unilateral Nephrectomy

Renin-angiotensin system (RAS) is a powerful modulator of renal hemodynamic and fluid homeostasis. Up-regulation in components of intra-renal RAS occurs with ageing. Recently we reported that 2 year old uninephrectomised (uni-x) female sheep have low renin hypertension and reduced renal function. By...

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Detalles Bibliográficos
Autores principales: Singh, Reetu R., Lankadeva, Yugeesh R., Denton, Kate M., Moritz, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698080/
https://www.ncbi.nlm.nih.gov/pubmed/23840884
http://dx.doi.org/10.1371/journal.pone.0068036