The admixture maximum likelihood test to test for association between rare variants and disease phenotypes

BACKGROUND: The development of genotyping arrays containing hundreds of thousands of rare variants across the genome and advances in high-throughput sequencing technologies have made feasible empirical genetic association studies to search for rare disease susceptibility alleles. As single variant t...

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Detalles Bibliográficos
Autores principales: Tyrer, Jonathan P, Guo, Qi, Easton, Douglas F, Pharoah, Paul DP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698090/
https://www.ncbi.nlm.nih.gov/pubmed/23738568
http://dx.doi.org/10.1186/1471-2105-14-177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698090/
https://www.ncbi.nlm.nih.gov/pubmed/23738568
http://dx.doi.org/10.1186/1471-2105-14-177

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