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The admixture maximum likelihood test to test for association between rare variants and disease phenotypes
BACKGROUND: The development of genotyping arrays containing hundreds of thousands of rare variants across the genome and advances in high-throughput sequencing technologies have made feasible empirical genetic association studies to search for rare disease susceptibility alleles. As single variant t...
Autores principales: | Tyrer, Jonathan P, Guo, Qi, Easton, Douglas F, Pharoah, Paul DP |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698090/ https://www.ncbi.nlm.nih.gov/pubmed/23738568 http://dx.doi.org/10.1186/1471-2105-14-177 |
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