GRG5/AES Interacts with T-Cell Factor 4 (TCF4) and Downregulates Wnt Signaling in Human Cells and Zebrafish Embryos

Transcriptional control by TCF/LEF proteins is crucial in key developmental processes such as embryo polarity, tissue architecture and cell fate determination. TCFs associate with β-catenin to activate transcription in the presence of Wnt signaling, but in its absence act as repressors together with...

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Detalles Bibliográficos
Autores principales: Costa, Ângela M. Sousa, Pereira-Castro, Isabel, Ricardo, Elisabete, Spencer, Forrest, Fisher, Shannon, da Costa, Luís Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698143/
https://www.ncbi.nlm.nih.gov/pubmed/23840876
http://dx.doi.org/10.1371/journal.pone.0067694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698143/
https://www.ncbi.nlm.nih.gov/pubmed/23840876
http://dx.doi.org/10.1371/journal.pone.0067694

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