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GRG5/AES Interacts with T-Cell Factor 4 (TCF4) and Downregulates Wnt Signaling in Human Cells and Zebrafish Embryos
Transcriptional control by TCF/LEF proteins is crucial in key developmental processes such as embryo polarity, tissue architecture and cell fate determination. TCFs associate with β-catenin to activate transcription in the presence of Wnt signaling, but in its absence act as repressors together with...
Autores principales: | Costa, Ângela M. Sousa, Pereira-Castro, Isabel, Ricardo, Elisabete, Spencer, Forrest, Fisher, Shannon, da Costa, Luís Teixeira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698143/ https://www.ncbi.nlm.nih.gov/pubmed/23840876 http://dx.doi.org/10.1371/journal.pone.0067694 |
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