A Cleavable N-Terminal Signal Peptide Promotes Widespread Olfactory Receptor Surface Expression in HEK293T Cells

Olfactory receptors (ORs) are G protein-coupled receptors that detect odorants in the olfactory epithelium, and comprise the largest gene family in the genome. Identification of OR ligands typically requires OR surface expression in heterologous cells; however, ORs rarely traffic to the cell surface...

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Detalles Bibliográficos
Autores principales: Shepard, Blythe D., Natarajan, Niranjana, Protzko, Ryan J., Acres, Omar W., Pluznick, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698168/
https://www.ncbi.nlm.nih.gov/pubmed/23840901
http://dx.doi.org/10.1371/journal.pone.0068758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698168/
https://www.ncbi.nlm.nih.gov/pubmed/23840901
http://dx.doi.org/10.1371/journal.pone.0068758

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