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A Cleavable N-Terminal Signal Peptide Promotes Widespread Olfactory Receptor Surface Expression in HEK293T Cells
Olfactory receptors (ORs) are G protein-coupled receptors that detect odorants in the olfactory epithelium, and comprise the largest gene family in the genome. Identification of OR ligands typically requires OR surface expression in heterologous cells; however, ORs rarely traffic to the cell surface...
Autores principales: | Shepard, Blythe D., Natarajan, Niranjana, Protzko, Ryan J., Acres, Omar W., Pluznick, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698168/ https://www.ncbi.nlm.nih.gov/pubmed/23840901 http://dx.doi.org/10.1371/journal.pone.0068758 |
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