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Caspase-2 Short Isoform Interacts with Membrane-Associated Cytoskeleton Proteins to Inhibit Apoptosis

Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspases activated by various stimuli. The casp-2 gene produces several alternative splicing isoforms. It is believed that the long isoform, casp-2L, promotes apoptosis, whereas the short isoform, casp-2S, i...

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Detalles Bibliográficos
Autores principales: Han, Chunhua, Zhao, Ran, Kroger, John, Qu, Meihua, Wani, Altaf A., Wang, Qi-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698186/
https://www.ncbi.nlm.nih.gov/pubmed/23840868
http://dx.doi.org/10.1371/journal.pone.0067033