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Examination of MARCO Activity on Dendritic Cell Phenotype and Function Using a Gene Knockout Mouse

We have reported the upregulation of MARCO, a member of the class A scavenger receptor family, on the surface of murine and human dendritic cells (DCs) pulsed with tumor lysates. Exposure of murine tumor lysate-pulsed DCs to an anti-MARCO antibody led to loss of dendritic-like processes and enhanced...

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Detalles Bibliográficos
Autores principales: Komine, Hiroshi, Kuhn, Lisa, Matsushita, Norimasa, Mulé, James J., Pilon-Thomas, Shari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698187/
https://www.ncbi.nlm.nih.gov/pubmed/23840879
http://dx.doi.org/10.1371/journal.pone.0067795