Human DDX3 Interacts with the HIV-1 Tat Protein to Facilitate Viral mRNA Translation

Nuclear export and translation of intron-containing viral mRNAs are required for HIV-1 gene expression and replication. In this report, we provide evidence to show that DDX3 regulates the translation of HIV-1 mRNAs. We found that knockdown of DDX3 expression effectively inhibited HIV-1 production. T...

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Detalles Bibliográficos
Autores principales: Lai, Ming-Chih, Wang, Shainn-Wei, Cheng, Lie, Tarn, Woan-Yuh, Tsai, Shaw-Jenq, Sun, H. Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698215/
https://www.ncbi.nlm.nih.gov/pubmed/23840900
http://dx.doi.org/10.1371/journal.pone.0068665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698215/
https://www.ncbi.nlm.nih.gov/pubmed/23840900
http://dx.doi.org/10.1371/journal.pone.0068665

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