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The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis

BACKGROUND: How cells decipher the duration of an external signal into different transcriptional outcomes is poorly understood. The hormone gastrin can promote a variety of cellular responses including proliferation, differentiation, migration and anti-apoptosis. While gastrin in normal concentratio...

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Detalles Bibliográficos
Autores principales: Selvik, Linn-Karina M, Fjeldbo, Christina S, Flatberg, Arnar, Steigedal, Tonje S, Misund, Kristine, Anderssen, Endre, Doseth, Berit, Langaas, Mette, Tripathi, Sushil, Beisvag, Vidar, Lægreid, Astrid, Thommesen, Liv, Bruland, Torunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698217/
https://www.ncbi.nlm.nih.gov/pubmed/23805861
http://dx.doi.org/10.1186/1471-2164-14-429