A method to achieve homogeneous dispersion of large transmembrane complexes within the holes of carbon films for electron cryomicroscopy

Difficulties associated with using X-ray crystallography for structural studies of large macromolecular complexes have made single particle cryo-electron microscopy (cryoEM) a key technique in structural biology. The efficient application of the single particle cryoEM approach requires the sample to...

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Detalles Bibliográficos
Autores principales: Cheung, Martin, Kajimura, Naoko, Makino, Fumiaki, Ashihara, Masamichi, Miyata, Tomoko, Kato, Takayuki, Namba, Keiichi, Blocker, Ariel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698441/
https://www.ncbi.nlm.nih.gov/pubmed/23356983
http://dx.doi.org/10.1016/j.jsb.2013.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698441/
https://www.ncbi.nlm.nih.gov/pubmed/23356983
http://dx.doi.org/10.1016/j.jsb.2013.01.004

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