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Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver()()()

Poor prenatal nutrition, acting through epigenetic processes, induces persistent changes in offspring phenotype. We investigated the effect of maternal fat intake on polyunsaturated fatty acid (PUFA) status and on the epigenetic regulation of Fads2, encoding Δ6 desaturase (rate limiting in PUFA synt...

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Detalles Bibliográficos
Autores principales: Hoile, Samuel P., Irvine, Nicola A., Kelsall, Christopher J., Sibbons, Charlene, Feunteun, Aurélie, Collister, Alex, Torrens, Christopher, Calder, Philip C., Hanson, Mark A., Lillycrop, Karen A., Burdge, Graham C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698442/
https://www.ncbi.nlm.nih.gov/pubmed/23107313
http://dx.doi.org/10.1016/j.jnutbio.2012.09.005