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Cancer translocations in human cells induced by zinc finger and TALE nucleases

Chromosomal translocations are signatures of numerous cancers and lead to expression of fusion genes that act as oncogenes. The wealth of genomic aberrations found in cancer, however, makes it challenging to assign a specific phenotypic change to a specific aberration. In this study, we set out to u...

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Detalles Bibliográficos
Autores principales: Piganeau, Marion, Ghezraoui, Hind, De Cian, Anne, Guittat, Lionel, Tomishima, Mark, Perrouault, Loic, René, Oliver, Katibah, George E., Zhang, Lei, Holmes, Michael C., Doyon, Yannick, Concordet, Jean-Paul, Giovannangeli, Carine, Jasin, Maria, Brunet, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698511/
https://www.ncbi.nlm.nih.gov/pubmed/23568838
http://dx.doi.org/10.1101/gr.147314.112