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Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID

Somatic hypermutation (SHM) of Ig genes is initiated by the activation-induced cytidine deaminase (AID), and requires target gene transcription. We previously proposed that AID may associate with the RNA polymerase II (Pol). Here, to determine aspects of the transcription process required for SHM, w...

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Detalles Bibliográficos
Autores principales:	Kodgire, Prashant, Mukkawar, Priyanka, Ratnam, Sarayu, Martin, Terence E., Storb, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698518/ https://www.ncbi.nlm.nih.gov/pubmed/23752228 http://dx.doi.org/10.1084/jem.20121523

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