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PDGFRα and CD51 mark human Nestin(+) sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

The intermediate filament protein Nestin labels populations of stem/progenitor cells, including self-renewing mesenchymal stem cells (MSCs), a major constituent of the hematopoietic stem cell (HSC) niche. However, the intracellular location of Nestin prevents its use for prospective live cell isolat...

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Detalles Bibliográficos
Autores principales: Pinho, Sandra, Lacombe, Julie, Hanoun, Maher, Mizoguchi, Toshihide, Bruns, Ingmar, Kunisaki, Yuya, Frenette, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698522/
https://www.ncbi.nlm.nih.gov/pubmed/23776077
http://dx.doi.org/10.1084/jem.20122252