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PDGFRα and CD51 mark human Nestin(+) sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
The intermediate filament protein Nestin labels populations of stem/progenitor cells, including self-renewing mesenchymal stem cells (MSCs), a major constituent of the hematopoietic stem cell (HSC) niche. However, the intracellular location of Nestin prevents its use for prospective live cell isolat...
Autores principales: | Pinho, Sandra, Lacombe, Julie, Hanoun, Maher, Mizoguchi, Toshihide, Bruns, Ingmar, Kunisaki, Yuya, Frenette, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698522/ https://www.ncbi.nlm.nih.gov/pubmed/23776077 http://dx.doi.org/10.1084/jem.20122252 |
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