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Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity

Reliable biomarkers corresponding to disease progression or therapeutic responsiveness in multiple sclerosis (MS) have not been yet identified. We previously reported that low expression of the antiproliferative gene TOB1 in CD4(+) T cells of individuals presenting with an initial central nervous sy...

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Detalles Bibliográficos
Autores principales: Schulze-Topphoff, Ulf, Casazza, Simona, Varrin-Doyer, Michel, Pekarek, Kara, Sobel, Raymond A., Hauser, Stephen L., Oksenberg, Jorge R., Zamvil, Scott S., Baranzini, Sergio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698524/
https://www.ncbi.nlm.nih.gov/pubmed/23797093
http://dx.doi.org/10.1084/jem.20121611