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Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity
Reliable biomarkers corresponding to disease progression or therapeutic responsiveness in multiple sclerosis (MS) have not been yet identified. We previously reported that low expression of the antiproliferative gene TOB1 in CD4(+) T cells of individuals presenting with an initial central nervous sy...
Autores principales: | Schulze-Topphoff, Ulf, Casazza, Simona, Varrin-Doyer, Michel, Pekarek, Kara, Sobel, Raymond A., Hauser, Stephen L., Oksenberg, Jorge R., Zamvil, Scott S., Baranzini, Sergio E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698524/ https://www.ncbi.nlm.nih.gov/pubmed/23797093 http://dx.doi.org/10.1084/jem.20121611 |
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