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Guanylate cyclase C signaling: an intestinal secretory pathway where bugs, genes and new drugs intersect

Acute infectious and chronic diarrheal diseases are important public health problems. A recent study by Fiskerstrand and colleagues identified a family with a rare early onset familial diarrhea. By linkage analysis and exon sequencing, the authors identified a heterozygous missense mutation in GUCY2...

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Detalles Bibliográficos
Autor principal: Camilleri, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698531/
https://www.ncbi.nlm.nih.gov/pubmed/22734671
http://dx.doi.org/10.1186/gm349