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Cannabinoids inhibit energetic metabolism and induce AMPK-dependent autophagy in pancreatic cancer cells

The anti-tumoral effects of cannabinoids have been described in different tumor systems, including pancreatic adenocarcinoma, but their mechanism of action remains unclear. We used cannabinoids specific for the CB1 (ACPA) and CB2 (GW) receptors and metabolomic analyses to unravel the potential pathw...

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Detalles Bibliográficos
Autores principales: Dando, I, Donadelli, M, Costanzo, C, Dalla Pozza, E, D'Alessandro, A, Zolla, L, Palmieri, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698539/
https://www.ncbi.nlm.nih.gov/pubmed/23764845
http://dx.doi.org/10.1038/cddis.2013.151