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Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation

Idiopathic pulmonary fibrosis (IPF) is a serious progressive and irreversible lung disease with unknown etiology and few treatment options. This disease was once thought to be a chronic inflammatory-driven process, but it is increasingly recognized that the epithelial–mesenchymal transition (EMT) co...

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Detalles Bibliográficos
Autores principales: Chen, Y-L, Zhang, X, Bai, J, Gai, L, Ye, X-L, Zhang, L, Xu, Q, Zhang, Y-X, Xu, L, Li, H-P, Ding, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698540/
https://www.ncbi.nlm.nih.gov/pubmed/23764846
http://dx.doi.org/10.1038/cddis.2013.154