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Protogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the α5β1-integrin

The bones and connective tissues of the murine jaws and skull are partly derived from cephalic neural crest cells (CNCCs). Here, we report that mice deficient of protogenin (Prtg) protein, an immunoglobulin domain-containing receptor expressed in the developing nervous system, have impairments of th...

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Detalles Bibliográficos
Autores principales: Wang, Y-C, Juan, H-C, Wong, Y-H, Kuo, W-C, Lu, Y-L, Lin, S-F, Lu, C-J, Fann, M-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698544/
https://www.ncbi.nlm.nih.gov/pubmed/23744351
http://dx.doi.org/10.1038/cddis.2013.177