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Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis
Resting tumor cells represent a huge challenge during anticancer therapy due to their increased treatment resistance. TNF-related apoptosis-inducing ligand (TRAIL) is a putative future anticancer drug, currently in phases I and II clinical studies. We recently showed that TRAIL is able to target leu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698546/ https://www.ncbi.nlm.nih.gov/pubmed/23744361 http://dx.doi.org/10.1038/cddis.2013.179 |