Cargando…

Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis

Resting tumor cells represent a huge challenge during anticancer therapy due to their increased treatment resistance. TNF-related apoptosis-inducing ligand (TRAIL) is a putative future anticancer drug, currently in phases I and II clinical studies. We recently showed that TRAIL is able to target leu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ehrhardt, H, Wachter, F, Grunert, M, Jeremias, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698546/ https://www.ncbi.nlm.nih.gov/pubmed/23744361 http://dx.doi.org/10.1038/cddis.2013.179

Ejemplares similares

Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling
por: Wachter, Franziska, et al.
Publicado: (2013)

Combination Therapy of TRAIL and Thymoquinone Induce Breast Cancer Cell Cytotoxicity-Mediated Apoptosis and Cell Cycle Arrest
por: Abdel Salam, Nagwa M, et al.
Publicado: (2021)

Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis
por: Voss, Oliver H., et al.
Publicado: (2021)

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL
por: Chen, Qing-Zhou, et al.
Publicado: (2020)

The adaptor protein FADD and the initiator caspase-8 mediate activation of NF-κB by TRAIL
por: Grunert, M, et al.
Publicado: (2012)

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis
por: Chan, David Y. L., et al.
Publicado: (2007)

Andrographolide sensitizes prostate cancer cells to TRAIL-induced apoptosis
por: Wei, Ruo-Jing, et al.
Publicado: (2018)

Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis
por: Ren, Yu, et al.
Publicado: (2021)

Zebularine and trichostatin A sensitized human breast adenocarcinoma cells towards tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis
por: Kong, Wei Yang, et al.
Publicado: (2019)

Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer Cells
por: Trivedi, Rachana, et al.
Publicado: (2015)

Light‐Controlled Cell‐Cycle Arrest and Apoptosis
por: Uhl, Edgar, et al.
Publicado: (2020)

Mechanisms of Cell Cycle Arrest and Apoptosis in Glioblastoma
por: Gousias, Konstantinos, et al.
Publicado: (2022)

Withanolide E sensitizes renal carcinoma cells to TRAIL-induced apoptosis by increasing cFLIP degradation
por: Henrich, C J, et al.
Publicado: (2015)

Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs
por: Nalli, Ancy D., et al.
Publicado: (2018)

Bufalin sensitizes human bladder carcinoma cells to TRAIL-mediated apoptosis
por: Kang, Kyung-Hwa, et al.
Publicado: (2017)

Scorpion (Androctonus bicolor) venom exhibits cytotoxicity and induces cell cycle arrest and apoptosis in breast and colorectal cancer cell lines
por: Al-Asmari, Abdulrahman K., et al.
Publicado: (2016)

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline
por: Zinnah, K.M.A., et al.
Publicado: (2021)

Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (Trail) Is an Inhibitor of Autoimmune Inflammation and Cell Cycle Progression
por: Song, Kaimei, et al.
Publicado: (2000)

Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
por: Luo, Yin, et al.
Publicado: (2023)

Analgecine enhances the anti-tumor response of radiotherapy by increasing apoptosis and cell cycle arrest in non-small cell lung cancer
por: Chen, Xue, et al.
Publicado: (2017)

Haloperidol Induced Cell Cycle Arrest and Apoptosis in Glioblastoma Cells
por: Papadopoulos, Fotios, et al.
Publicado: (2020)

Inhibition of tumor cell growth by adenine is mediated by apoptosis induction and cell cycle S phase arrest
por: Han, Ming, et al.
Publicado: (2017)

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism
por: Lincoln, Frank A., et al.
Publicado: (2018)

Histone Deacetylase Inhibitors Sensitize TRAIL-Induced Apoptosis in Colon Cancer Cells
por: Zhang, Baojie, et al.
Publicado: (2019)

Paris Saponin I Sensitizes Gastric Cancer Cell Lines to Cisplatin via Cell Cycle Arrest and Apoptosis
por: Song, Shuichuan, et al.
Publicado: (2016)

Dietary Flavonoids Sensitize HeLa Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)
por: Szliszka, Ewelina, et al.
Publicado: (2008)

The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis
por: Morissette, Mathieu C, et al.
Publicado: (2011)

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells
por: Florean, Cristina, et al.
Publicado: (2016)

Sorbus rufopilosa Extract Exhibits Antioxidant and Anticancer Activities by Inducing Cell Cycle Arrest and Apoptosis in Human Colon Adenocarcinoma HT29 Cells
por: Oh, You Na, et al.
Publicado: (2016)

Acetonitrile extract of Salvia miltiorrhiza Radix exhibits growth-inhibitory effects on prostate cancer cells through the induction of cell cycle arrest and apoptosis
por: Lee, June, et al.
Publicado: (2017)

In vitro and in vivo anticancer studies of 2'-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by HDAC inhibition and cell cycle arrest
por: Pande, Aditya Narayan, et al.
Publicado: (2017)

EGFR inhibitors sensitize non–small cell lung cancer cells to TRAIL-induced apoptosis
por: Xu, Fei, et al.
Publicado: (2011)

[Retracted] Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL‑mediated apoptosis
por: Yoshiba, Sayaka, et al.
Publicado: (2023)

Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells
por: Madhok, B M, et al.
Publicado: (2010)

Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression
por: Sant, David W., et al.
Publicado: (2018)

Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis
por: Hague, A, et al.
Publicado: (2005)

Down-Regulation of Survivin by Nemadipine-A Sensitizes Cancer Cells to TRAIL-Induced Apoptosis
por: Park, Seong Ho, et al.
Publicado: (2013)

Apigenin Sensitizes Huh-7 Human Hepatocellular Carcinoma Cells to TRAIL-induced Apoptosis
por: Kim, Eun Young, et al.
Publicado: (2012)

ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis
por: Quast, S-A, et al.
Publicado: (2013)

Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis
por: Notaro, Antonietta, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vlpb6r4kr1erhb4tvaq1iih1gk