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Cell cycle-arrested tumor cells exhibit increased sensitivity towards TRAIL-induced apoptosis

Resting tumor cells represent a huge challenge during anticancer therapy due to their increased treatment resistance. TNF-related apoptosis-inducing ligand (TRAIL) is a putative future anticancer drug, currently in phases I and II clinical studies. We recently showed that TRAIL is able to target leu...

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Detalles Bibliográficos
Autores principales:	Ehrhardt, H, Wachter, F, Grunert, M, Jeremias, I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698546/ https://www.ncbi.nlm.nih.gov/pubmed/23744361 http://dx.doi.org/10.1038/cddis.2013.179

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