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Glycation exacerbates the neuronal toxicity of β-amyloid

Accumulation evidence shows that β-amyloid (Aβ) is a neurotoxic and accumulation of Aβ is responsible for the pathology of Alzheimer's disease (AD). However, it is currently not fully understood what makes Aβ toxic and accumulated. Previous studies demonstrate that Aβ is a suitable substrate fo...

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Detalles Bibliográficos
Autores principales: Li, X-H, Du, L-L, Cheng, X-S, Jiang, X, Zhang, Y, Lv, B-L, Liu, R, Wang, J-Z, Zhou, X-W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698547/
https://www.ncbi.nlm.nih.gov/pubmed/23764854
http://dx.doi.org/10.1038/cddis.2013.180