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CHIP has a protective role against oxidative stress-induced cell death through specific regulation of Endonuclease G

Oxidative stress is implicated in carcinogenesis, aging, and neurodegenerative diseases. The E3 ligase C terminus of Hsc-70 interacting protein (CHIP) has a protective role against various stresses by targeting damaged proteins for proteasomal degradation, and thus maintains protein quality control....

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Detalles Bibliográficos
Autores principales:	Lee, J S, Seo, T W, Yi, J H, Shin, K S, Yoo, S J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698548/ https://www.ncbi.nlm.nih.gov/pubmed/23764847 http://dx.doi.org/10.1038/cddis.2013.181

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