A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma

Engagement of the mitochondrial-death amplification pathway is an essential component in chemotherapeutic execution of cancer cells. Therefore, identification of mitochondria-targeting agents has become an attractive avenue for novel drug discovery. Here, we report the anticancer activity of a novel...

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Detalles Bibliográficos
Autores principales: Maillet, A, Yadav, S, Loo, Y L, Sachaphibulkij, K, Pervaiz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698552/
https://www.ncbi.nlm.nih.gov/pubmed/23744353
http://dx.doi.org/10.1038/cddis.2013.185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698552/
https://www.ncbi.nlm.nih.gov/pubmed/23744353
http://dx.doi.org/10.1038/cddis.2013.185

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