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Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation

The B″/PR72 family of protein phosphatase 2A (PP2A) is an important PP2A family involved in diverse cellular processes, and uniquely regulated by calcium binding to the regulatory subunit. The PR70 subunit in this family interacts with cell division control 6 (Cdc6), a cell cycle regulator important...

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Detalles Bibliográficos
Autores principales: Wlodarchak, Nathan, Guo, Feng, Satyshur, Kenneth A, Jiang, Li, Jeffrey, Philip D, Sun, Tingwan, Stanevich, Vitali, Mumby, Marc C, Xing, Yongna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698643/
https://www.ncbi.nlm.nih.gov/pubmed/23752926
http://dx.doi.org/10.1038/cr.2013.77