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Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation
The B″/PR72 family of protein phosphatase 2A (PP2A) is an important PP2A family involved in diverse cellular processes, and uniquely regulated by calcium binding to the regulatory subunit. The PR70 subunit in this family interacts with cell division control 6 (Cdc6), a cell cycle regulator important...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698643/ https://www.ncbi.nlm.nih.gov/pubmed/23752926 http://dx.doi.org/10.1038/cr.2013.77 |