Cargando…
Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation
The B″/PR72 family of protein phosphatase 2A (PP2A) is an important PP2A family involved in diverse cellular processes, and uniquely regulated by calcium binding to the regulatory subunit. The PR70 subunit in this family interacts with cell division control 6 (Cdc6), a cell cycle regulator important...
Autores principales: | Wlodarchak, Nathan, Guo, Feng, Satyshur, Kenneth A, Jiang, Li, Jeffrey, Philip D, Sun, Tingwan, Stanevich, Vitali, Mumby, Marc C, Xing, Yongna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698643/ https://www.ncbi.nlm.nih.gov/pubmed/23752926 http://dx.doi.org/10.1038/cr.2013.77 |
Ejemplares similares
-
Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone
por: Guo, Feng, et al.
Publicado: (2014) -
Mechanisms of the Scaffold Subunit in Facilitating Protein Phosphatase 2A Methylation
por: Stanevich, Vitali, et al.
Publicado: (2014) -
Methylation-regulated decommissioning of multimeric PP2A complexes
por: Wu, Cheng-Guo, et al.
Publicado: (2017) -
Structural basis of protein phosphatase 2A stable latency
por: Jiang, Li, et al.
Publicado: (2013) -
Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers
por: Williams, Byron C, et al.
Publicado: (2014)