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Pausing for thought: Disrupting the early transcription elongation checkpoint leads to developmental defects and tumourigenesis

Factors affecting transcriptional elongation have been characterized extensively in in vitro, single cell (yeast) and cell culture systems; however, data from the context of multicellular organisms has been relatively scarce. While studies in homogeneous cell populations have been highly informative...

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Detalles Bibliográficos
Autor principal: Jennings, Barbara H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698693/
https://www.ncbi.nlm.nih.gov/pubmed/23575664
http://dx.doi.org/10.1002/bies.201200179