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Arachidonic Acid–Induced Dilation in Human Coronary Arterioles: Convergence of Signaling Mechanisms on Endothelial TRPV4‐Mediated Ca(2+) Entry

BACKGROUND: Arachidonic acid (AA) and/or its enzymatic metabolites are important lipid mediators contributing to endothelium‐derived hyperpolarizing factor (EDHF)–mediated dilation in multiple vascular beds, including human coronary arterioles (HCAs). However, the mechanisms of action of these lipid...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaodong, Zinkevich, Natalya S., Gebremedhin, Debebe, Gauthier, Kathryn M., Nishijima, Yoshinori, Fang, Juan, Wilcox, David A., Campbell, William B., Gutterman, David D., Zhang, David X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698766/
https://www.ncbi.nlm.nih.gov/pubmed/23619744
http://dx.doi.org/10.1161/JAHA.113.000080