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Deficiency of TDAG51 Protects Against Atherosclerosis by Modulating Apoptosis, Cholesterol Efflux, and Peroxiredoxin‐1 Expression

BACKGROUND: Apoptosis caused by endoplasmic reticulum (ER) stress contributes to atherothrombosis, the underlying cause of cardiovascular disease (CVD). T‐cell death‐associated gene 51 (TDAG51), a member of the pleckstrin homology‐like domain gene family, is induced by ER stress, causes apoptosis wh...

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Detalles Bibliográficos
Autores principales: Hossain, Gazi S., Lynn, Edward G., Maclean, Kenneth N., Zhou, Ji, Dickhout, Jeffrey G., Lhoták, Šárka, Trigatti, Bernardo, Capone, John, Rho, Jaerang, Tang, Damu, McCulloch, Christopher A., Al‐Bondokji, Imtisal, Malloy, Mary J., Pullinger, Clive R., Kane, John P., Li, Yonghong, Shiffman, Dov, Austin, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698773/
https://www.ncbi.nlm.nih.gov/pubmed/23686369
http://dx.doi.org/10.1161/JAHA.113.000134