Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts

BACKGROUND: The efficacy of pharmacological interventions to prevent sudden arrhythmic death in patients with chronic heart failure remains limited. Evidence now suggests increased ventricular expression of hyperpolarization‐activated cation (HCN) channels in hypertrophied and failing hearts contrib...

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Detalles Bibliográficos
Autores principales: Kuwabara, Yoshihiro, Kuwahara, Koichiro, Takano, Makoto, Kinoshita, Hideyuki, Arai, Yuji, Yasuno, Shinji, Nakagawa, Yasuaki, Igata, Sachiyo, Usami, Satoru, Minami, Takeya, Yamada, Yuko, Nakao, Kazuhiro, Yamada, Chinatsu, Shibata, Junko, Nishikimi, Toshio, Ueshima, Kenji, Nakao, Kazuwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698776/
https://www.ncbi.nlm.nih.gov/pubmed/23709563
http://dx.doi.org/10.1161/JAHA.113.000150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698776/
https://www.ncbi.nlm.nih.gov/pubmed/23709563
http://dx.doi.org/10.1161/JAHA.113.000150

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