Deletion of Phd2 in Myeloid Lineage Attenuates Hypertensive Cardiovascular Remodeling

BACKGROUND: Hypertension induces cardiovascular hypertrophy and fibrosis. Infiltrated macrophages are critically involved in this process. We recently reported that inhibition of prolyl hydroxylase domain protein 2 (PHD2), which hydroxylates the proline residues of hypoxia‐inducible factor‐α (HIF‐α)...

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Detalles Bibliográficos
Autores principales: Ikeda, Jiro, Ichiki, Toshihiro, Matsuura, Hirohide, Inoue, Eriko, Kishimoto, Junji, Watanabe, Aya, Sankoda, Chikahiro, Kitamoto, Shiro, Tokunou, Tomotake, Takeda, Kotaro, Fong, Guo‐Hua, Sunagawa, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698781/
https://www.ncbi.nlm.nih.gov/pubmed/23778187
http://dx.doi.org/10.1161/JAHA.113.000178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698781/
https://www.ncbi.nlm.nih.gov/pubmed/23778187
http://dx.doi.org/10.1161/JAHA.113.000178

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