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On the Origin of the Eukaryotic Chromosome: The Role of Noncanonical DNA Structures in Telomere Evolution

The transition of an ancestral circular genome to multiple linear chromosomes was crucial for eukaryogenesis because it allowed rapid adaptive evolution through aneuploidy. Here, we propose that the ends of nascent linear chromosomes should have had a dual function in chromosome end protection (capp...

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Detalles Bibliográficos
Autores principales: Garavís, Miguel, González, Carlos, Villasante, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698924/
https://www.ncbi.nlm.nih.gov/pubmed/23699225
http://dx.doi.org/10.1093/gbe/evt079