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Microhomology-Mediated Intron Loss during Metazoan Evolution

How introns are lost from eukaryotic genomes during evolution remains an enigmatic question in biology. By comparative genome analysis of five Caenorhabditis and eight Drosophila species, we found that the likelihood of intron loss is highly influenced by the degree of sequence homology at exon–intr...

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Detalles Bibliográficos
Autores principales: van Schendel, Robin, Tijsterman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698931/
https://www.ncbi.nlm.nih.gov/pubmed/23737326
http://dx.doi.org/10.1093/gbe/evt088