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Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia

An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 10(8) red blood cells, respectively. Maternal 6TGN levels could be useful i...

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Detalles Bibliográficos
Autores principales: Maruyama, Hidehiko, Tada, Katsuhiko, Fujiwara, Takuzo, Ota, Kosuke, Kageyama, Misao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699157/
https://www.ncbi.nlm.nih.gov/pubmed/23943705
http://dx.doi.org/10.1055/s-0032-1329683