Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia

An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 10(8) red blood cells, respectively. Maternal 6TGN levels could be useful i...

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Autores principales: Maruyama, Hidehiko, Tada, Katsuhiko, Fujiwara, Takuzo, Ota, Kosuke, Kageyama, Misao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2012
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699157/
https://www.ncbi.nlm.nih.gov/pubmed/23943705
http://dx.doi.org/10.1055/s-0032-1329683
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author Maruyama, Hidehiko
Tada, Katsuhiko
Fujiwara, Takuzo
Ota, Kosuke
Kageyama, Misao
author_facet Maruyama, Hidehiko
Tada, Katsuhiko
Fujiwara, Takuzo
Ota, Kosuke
Kageyama, Misao
author_sort Maruyama, Hidehiko
collection PubMed
description An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 10(8) red blood cells, respectively. Maternal 6TGN levels could be useful in predicting neonatal pancytopenia.
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spelling pubmed-36991572013-08-13 Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia Maruyama, Hidehiko Tada, Katsuhiko Fujiwara, Takuzo Ota, Kosuke Kageyama, Misao AJP Rep Article An infant with pancytopenia was born to a mother who used the common immunosuppressant azathioprine (AZA). Maternal and neonatal blood levels of 6-thioguanine nucleotides (6TGN; metabolite of AZA) were 1890 and 1480 pmol/8 × 10(8) red blood cells, respectively. Maternal 6TGN levels could be useful in predicting neonatal pancytopenia. Thieme Medical Publishers 2012-12-03 2013-05 /pmc/articles/PMC3699157/ /pubmed/23943705 http://dx.doi.org/10.1055/s-0032-1329683 Text en © Thieme Medical Publishers
spellingShingle Article
Maruyama, Hidehiko
Tada, Katsuhiko
Fujiwara, Takuzo
Ota, Kosuke
Kageyama, Misao
Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title_full Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title_fullStr Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title_full_unstemmed Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title_short Utility of Maternal 6-Thioguanine Nucleotide Levels in Predicting Neonatal Pancytopenia
title_sort utility of maternal 6-thioguanine nucleotide levels in predicting neonatal pancytopenia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699157/
https://www.ncbi.nlm.nih.gov/pubmed/23943705
http://dx.doi.org/10.1055/s-0032-1329683
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