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Aberrant DNA methylation of ESR1 and p14ARF genes could be useful as prognostic indicators in osteosarcoma

Osteosarcoma (OS) is the eighth most common form of childhood and adolescence cancer. Approximately 10%–20% of patients present metastatic disease at diagnosis and the 5-year overall survival remains around 70% for nonmetastatic patients and around 30% for metastatic patients. Metastatic disease at...

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Detalles Bibliográficos
Autores principales: Sonaglio, Viviane, de Carvalho, Ana C, Toledo, Silvia R C, Salinas-Souza, Carolina, Carvalho, André L, Petrilli, Antonio S, de Camargo, Beatriz, Vettore, André L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699305/
https://www.ncbi.nlm.nih.gov/pubmed/23836983
http://dx.doi.org/10.2147/OTT.S44918