Targeting cancer cell-specific RNA interference by siRNA delivery using a complex carrier of affibody-displaying bio-nanocapsules and liposomes

BACKGROUND: Small interfering RNA (siRNA) has attracted attention in the field of nucleic acid medicine as a RNA interference (RNAi) application that leads to gene silencing due to specific messenger RNA (mRNA) destruction. However, since siRNA is unstable in blood and unable to cross the cell membr...

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Detalles Bibliográficos
Autores principales: Nishimura, Yuya, Mieda, Hiroaki, Ishii, Jun, Ogino, Chiaki, Fujiwara, Toshinobu, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699380/
https://www.ncbi.nlm.nih.gov/pubmed/23800313
http://dx.doi.org/10.1186/1477-3155-11-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699380/
https://www.ncbi.nlm.nih.gov/pubmed/23800313
http://dx.doi.org/10.1186/1477-3155-11-19

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