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High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

BACKGROUND: The demand of monospecific high affinity binding reagents, particularly monoclonal antibodies, has been steadily increasing over the last years. Enhanced throughput of antibody generation has been addressed by optimizing in vitro selection using phage display which moved the major bottle...

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Detalles Bibliográficos
Autores principales: Jäger, Volker, Büssow, Konrad, Wagner, Andreas, Weber, Susanne, Hust, Michael, Frenzel, André, Schirrmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699382/
https://www.ncbi.nlm.nih.gov/pubmed/23802841
http://dx.doi.org/10.1186/1472-6750-13-52