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High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells
BACKGROUND: The demand of monospecific high affinity binding reagents, particularly monoclonal antibodies, has been steadily increasing over the last years. Enhanced throughput of antibody generation has been addressed by optimizing in vitro selection using phage display which moved the major bottle...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699382/ https://www.ncbi.nlm.nih.gov/pubmed/23802841 http://dx.doi.org/10.1186/1472-6750-13-52 |