Constitutional CHEK2 mutations are infrequent in early-onset and familial breast/ovarian cancer patients from Pakistan

BACKGROUND: Less than 20% of Pakistani women with early-onset or familial breast/ovarian cancer harbor germ line mutations in the high-penetrance genes BRCA1, BRCA2 and TP53. Thus, mutations in other genes confer genetic susceptibility to breast cancer, of which CHEK2 is a plausible candidate. CHEK2...

Descripción completa

Detalles Bibliográficos
Autores principales: Rashid, Muhammad U, Muhammad, Noor, Faisal, Saima, Amin, Asim, Hamann, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699428/
https://www.ncbi.nlm.nih.gov/pubmed/23806170
http://dx.doi.org/10.1186/1471-2407-13-312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699428/
https://www.ncbi.nlm.nih.gov/pubmed/23806170
http://dx.doi.org/10.1186/1471-2407-13-312

Ejemplares similares