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ROADMAP and ORIENTAL Trials: the Re-emergence of J-Curve Ghost?

It still remains unknown whether angiotensin-receptor blockers (ARBs) are cardioprotective in patients with type 2 diabetes. The recent two clinical trials, the ROADMAP and the ORIENT, have suggested that fatal cardiovascular events or cardiovascular deaths were unexpectedly higher in olmesartan gro...

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Detalles Bibliográficos
Autores principales: Hamamoto, Yoshiyuki, Koshiyama, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699452/
https://www.ncbi.nlm.nih.gov/pubmed/23885187
http://dx.doi.org/10.4137/JCM.S7521