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DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE)

BACKGROUND: DJ-1 is found in many tissues, including the brain, where it has been extensively studied due to its association with Parkinson’s disease. DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress. METHODOLOGY:...

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Detalles Bibliográficos
Autores principales: Shadrach, Karen G., Rayborn, Mary E., Hollyfield, Joe G., Bonilha, Vera L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699467/
https://www.ncbi.nlm.nih.gov/pubmed/23844142
http://dx.doi.org/10.1371/journal.pone.0067983