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DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE)
BACKGROUND: DJ-1 is found in many tissues, including the brain, where it has been extensively studied due to its association with Parkinson’s disease. DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress. METHODOLOGY:...
Autores principales: | Shadrach, Karen G., Rayborn, Mary E., Hollyfield, Joe G., Bonilha, Vera L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699467/ https://www.ncbi.nlm.nih.gov/pubmed/23844142 http://dx.doi.org/10.1371/journal.pone.0067983 |
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