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Suppressive Oligodeoxynucleotides Promote the Development of Th17 Cells

Synthetic oligonucleotides containing repetitive TTAGGG motifs mimic the immunosuppressive activity of telomeric DNA. These suppressive oligonucleotides (Sup ODN) are effective in the treatment/prevention of various inflammatory and autoimmune diseases in mice. The therapeutic activity of Sup ODN wa...

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Detalles Bibliográficos
Autores principales: Bode, Christian, Yang, Xiang-Ping, Kiu, Hiu, Klinman, Dennis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699503/
https://www.ncbi.nlm.nih.gov/pubmed/23844143
http://dx.doi.org/10.1371/journal.pone.0067991