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Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

Aberrant Wnt/β-catenin signaling has been strongly associated with the tumorigenesis of human colorectal cancer. Inhibitors of this pathway may then offer therapeutic strategies as well as chemoprevention for this malignant disease. Henryin is an ent-kaurane diterpenoid isolated from Isodon rubescen...

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Detalles Bibliográficos
Autores principales: Li, Xingyao, Pu, Jianxin, Jiang, Shiyou, Su, Jia, Kong, Lingmei, Mao, Bingyu, Sun, Handong, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699517/
https://www.ncbi.nlm.nih.gov/pubmed/23844215
http://dx.doi.org/10.1371/journal.pone.0068525