Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice

We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO(2) (−/)NO(3) (−) data from “middle-aged” (6–8 months old) C57BL/6 mice were used to re-parameterize...

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Detalles Bibliográficos
Autores principales: Namas, Rami A., Bartels, John, Hoffman, Rosemary, Barclay, Derek, Billiar, Timothy R., Zamora, Ruben, Vodovotz, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699569/
https://www.ncbi.nlm.nih.gov/pubmed/23844008
http://dx.doi.org/10.1371/journal.pone.0067419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699569/
https://www.ncbi.nlm.nih.gov/pubmed/23844008
http://dx.doi.org/10.1371/journal.pone.0067419

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